Domain 1 · ~10–15% of BASIC/ADVANCED

Clinical Sciences

Anatomy, physics, and pharmacology of anesthetic agents. The foundation everything else rests on. Induction agents, opioids, muscle relaxants, volatile anesthetics, regional anesthesia drugs.

Subtopics

AnatomyAirway anatomy, neuraxial & peripheral nerve anatomy, vascular access landmarks.
PhysicsGas laws, vaporizers, ventilator mechanics, monitoring physics, MRI safety.
Pharmacology — IV anestheticsPropofol, etomidate, ketamine, dexmedetomidine — PK/PD and clinical use.
Pharmacology — opioidsMorphine, fentanyl family, methadone — receptors, dosing, side effects.
Pharmacology — neuromuscular blockersDepolarizing vs non-depolarizing, reversal agents, monitoring.
Pharmacology — volatile anestheticsMAC, uptake/distribution, organ effects, malignant hyperthermia.
Pharmacology — local anestheticsMechanism, toxicity, additives, regional implications.

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